Mary&May - Spicule Retinol PDRN Cream

For initial use, apply every other night after cleansing. As your skin adapts, you can increase to nightly application. Always apply to clean, dry skin and follow with moisturizer if needed.

It's best to avoid using other strong exfoliants (like AHAs, BHAs) or harsh treatments on the same night. You can layer hydrating serums or moisturizers over it. Perform a patch test if combining with other new products.

The cream contains a soothing complex and is formulated to minimize irritation. However, due to the presence of retinol and spicules, individuals with very sensitive skin should perform a patch test first. Start with infrequent application.

The marine-derived spicules are microscopic, natural structures that are smaller than pores. They help to gently exfoliate the skin and create temporary micro-channels, which can enhance the absorption of other active ingredients like retinol and PDRN.

PDRN (Polydeoxyribonucleotide) is derived from Centella Asiatica and is known for its skin regeneration properties. It helps to repair damaged skin cells, promote wound healing, and support overall skin health and resilience.

Typically, unopened products have a shelf life of 2-3 years. Once opened, it's best to use within 12 months, provided it is stored correctly in a cool, dry place away from direct sunlight.

Retinol can increase photosensitivity. While this formula aims to minimize irritation, it is strongly recommended to use this cream at night. Always wear sunscreen during the day when using retinol products.

This is often a normal reaction to retinol. Try using it every other night initially or apply a smaller amount. Ensure your skin is fully dry before application and follow with a moisturizer. If irritation persists, discontinue use.

This sensation is likely due to the micro-spicules. Ensure you are spreading it evenly and gently pressing it into the skin to aid absorption. The texture should dissipate as the product absorbs.

Consistent, nightly use is key for retinol and PDRN products. Ensure you are applying the correct amount and integrating it properly into your skincare routine. Results can take 4-12 weeks to become apparent.

Ensure the product is stored correctly away from heat and light. Always seal the container tightly after use. If the product has been open for a long time or stored improperly, its efficacy may decrease.